A massive drug operation changes the lives of three conflicted New York cops. Burned-out vet Eddie Dugan (Richard Gere) is close to retirement; narcotics cop Sal Procida (Ethan Hawke) faces the difficult task of caring for his large family on his ordinary salary; undercover officer Clarence "Tango" Butler (Don Cheadle) finds his loyalties beginning to shift toward a powerful drug dealer. Over seven chaotic days, the three men are drawn toward a fateful crime and destiny.